Pharmacokinetics and pharmacodynamics of stereoisomeric drugs with particular reference to bioequivalence determination
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چکیده
منابع مشابه
Pharmacokinetics and pharmacodynamics of stereoisomeric drugs with particular reference to bioequivalence determination.
Drugs containing one or more chiral centres exist in stereoisomeric molecular forms. Most commonly, drugs containing a single asymmetric carbon atom exist in two enantiomeric forms, designated as eutomer (the more potent) and distomer (the less potent). As well as differences in potency and other pharmacodynamic properties, most members of enantiomeric pairs commonly differ also in their pharma...
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ژورنال
عنوان ژورنال: Journal of Veterinary Pharmacology and Therapeutics
سال: 2012
ISSN: 0140-7783
DOI: 10.1111/j.1365-2885.2012.01367.x